The Testosterone, Total, Males (Adult) Only assessment encompasses one test with a single biomarker.
Brief Overview:
This evaluation quantifies the aggregate amount of testosterone present in the bloodstream, with testosterone being a vital male hormone predominantly synthesized in the testicles. It plays a crucial role in the emergence of male sexual traits, reproductive capabilities, muscle build-up, bone strength, and general health and wellness.
Important Note: Should Testosterone, Total, Males (Adult) Only #873 be requisitioned for a pediatric subject or a female, the laboratory will promptly modify the test to Testosterone, Total, MS #15983 and adjust the billing accordingly.
Synonyms:
Testosterone Total Assessment, Male Testosterone Evaluation, Testosterone Examination for Males
Method of Collection:
Venipuncture
Type of Specimen:
Serum
Pre-test Requirements:
Fasting or special preparation is not necessary.
Given the diurnal variation in testosterone levels, The Endocrine Society advocates for two specimens to be collected in the morning hours (between 8:00 and 10:00 a.m.) across different dates for initial screening purposes.
This particular examination is capable of reporting testosterone values up to 3000 ng/dL, with any results exceeding this threshold being recorded as >3000.
The Testosterone Total Male Evaluation is Requested in Various Scenarios:
Assessment of Hormone Levels:
This test is frequently utilized to scrutinize testosterone levels and uncover any potential hormonal imbalances in men. Manifestations such as a diminished sexual drive, issues with maintaining an erection, persistent tiredness, changes in mood, loss of muscle strength, or challenges in conceiving may lead healthcare practitioners to examine testosterone concentrations.
Identifying Hypogonadism:
Hypogonadism is a medical condition characterized by inadequate testosterone production in the body. Utilizing the Testosterone Total Male assessment aids in diagnosing this condition and in strategizing effective treatment methodologies.
Observing Testosterone Supplementation:
For men undergoing testosterone replacement therapy, it is imperative to consistently track testosterone levels to confirm that the dosage is correct and that the treatment is yielding the desired results.
Testosterone is the predominant male sex hormone, playing a pivotal role in shaping a man’s physical attributes. This particular blood test is designed to quantify the testosterone concentration in an individual’s bloodstream.
Produced chiefly in the testicles’ Leydig cells, testosterone is also synthesized in small amounts by the adrenal glands in males. It facilitates the emergence of secondary sexual characteristics, including the development of male genitalia, the proliferation of body hair, muscle growth, and the deepening of the voice. Testosterone is crucial for maintaining libido, muscle mass, and overall vitality, especially during puberty and throughout adulthood.
The regulation of testosterone production involves the pituitary gland, which releases luteinizing hormone (LH) to stimulate and control the synthesis of testosterone. This interaction follows a negative feedback loop: elevated testosterone levels lead to decreased LH production, curbing further testosterone synthesis. Conversely, lower testosterone levels trigger an increase in LH production, stimulating testosterone synthesis.
Testosterone levels exhibit diurnal variation, peaking in the early morning hours and diminishing by the evening. Physical activity can cause levels to rise, while aging is generally associated with a decrease in testosterone.
In circulation, roughly two-thirds of testosterone is bound to sex-hormone binding globulin (SHBG), and one-third is attached to albumin. A minuscule fraction circulates as free testosterone. The sum of free and albumin-bound testosterone constitutes the bioavailable testosterone, capable of exerting effects on target tissues.
In numerous cases, measuring total testosterone provides adequate information for clinicians. However, in instances where SHBG levels are abnormal, assessing free or bioavailable testosterone might offer a more precise indication of the underlying condition.
Associated Laboratory Examinations with a Testosterone Total Male Test:
- Estradiol
- Dihydrotestosterone
- Follicle-Stimulating Hormone (FSH)
- Luteinizing Hormone (LH)
- Estrogens (Total or Fractionated)
- Estriol
- Estrone
- Albumin
- Prolactin
- Anti-Mullerian Hormone
- Androstenedione
- Sex Hormone Binding Globulin (SHBG)
These additional tests provide a comprehensive insight into a male’s hormonal balance and help in diagnosing and managing various conditions.
The Testosterone Total Male Test is Particularly Beneficial in Several Scenarios, Including:
1. Hypogonadism:
Characterized by low testosterone production, hypogonadism manifests through symptoms such as diminished libido, challenges in achieving erections, chronic fatigue, mood swings, muscle weakness, and fertility issues. This test is integral in diagnosing hypogonadism and tailoring treatment to the individual’s needs.
2. Andropause:
Commonly referred to as male menopause, andropause is associated with a natural decline in testosterone levels due to aging. This test aids in determining the necessity of hormone replacement therapy and in monitoring its effectiveness.
3. Hormonal Therapy Monitoring:
For individuals undergoing hormone treatments, such as transgender individuals or those using anabolic steroids, it is crucial to regularly monitor testosterone levels to ensure optimal dosing and to mitigate potential risks.
By utilizing the Testosterone Total Male test in these situations, healthcare providers can make well-informed decisions to enhance patient care and improve outcomes.